The European Association for Cancer Research (EACR)
By cancer researchers, for cancer researchers. Join us as we sit down with renowned researchers from around the world to discuss their personal experiences and ...
Cross-border collaboration is crucial in cancer research because it fosters knowledge-sharing, accelerates innovation, and maximises the impact of research by leveraging diverse expertise and resources. However, it also comes with many challenges.
In this episode of The Cancer Researcher Podcast we're joined by four renowned experts — the Director of EMBO, the Director of Research and Partnerships at Cancer Research UK, the Past President of the European Academy of Cancer Sciences, and the Past President of the EACR.
The guests discuss the complexities and benefits of cross-border collaboration in cancer research, emphasising the need for careful planning and understanding diverse funding models. They also explore the balance between discovery science and translational research, the importance of investigator-initiated and pragmatic clinical trials, and how such approaches can drive innovation and reduce healthcare costs.
🔗 Access transcripts for all our episodes at magazine.eacr.org/podcast.
🔗 Celis, J. and Ringborg, U. (2024), From the creation of the European research area in 2000 to a Mission on cancer in Europe in 2021-lessons learned and implications. Mol Oncol, 18: 785-792. https://doi.org/10.1002/1878-0261.13632
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47:25
Research focus: the impact of chronic stress on tumour progression
A cancer diagnosis is understandably stressful for a patient. But how does chronic stress influence cancer progression and metastasis? In this episode, Dr. Xue-Yan He discusses her recent research on the impact of stress on the tumour microenvironment, with a focus on the altered balance between neutrophils and lymphocytes and its role in promoting tumour spread.
This study, published in Cancer Cell (Volume 42, Pages 474–486), was selected for the EACR Highlights in Cancer Research, showcasing its significance to the field.
🔗 Read the Cancer Cell article: https://doi.org/10.1016/j.ccell.2024.01.013
🔗 Explore the EACR Highlights: https://magazine.eacr.org/highlights-in-cancer-research-june-2024/3/
🔗 Access transcripts for all our episodes at magazine.eacr.org/podcast.
Tune in for an in-depth discussion on the interplay between stress and cancer biology, and its implications for understanding tumour progression.
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Research focus: a novel pan-lysyl oxidase inhibitor for improving the treatment of pancreatic cancer
Dr. Jessica Chitty and Dr. Thomas Cox generated and validated a novel selective and irreversible pan-lysyl oxidase inhibitor: PXS-5505. Their experiments in a series of pre-clinical models show that by acting on the tumour microenvironment, this small molecule drug has the ability to significantly enhance chemotherapy efficacy.
Listen to this episode to find out direct from the authors about the effects that PXS-5505 in combination with gemcetabine has on tumour morphology, behaviour and subject survival in pancreatic cancer.
This study has been published in Nature Cancer and was included in the EACR's Highlights in Cancer Research, a summary of the most interesting and impactful recent papers in cancer research.
Access transcripts for all our episodes at magazine.eacr.org/podcast.
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Scientific management as a career
Have you ever wondered what it would be like to pursue a career in scientific management? What would a regular workday look like? What skills are valued in this sector and what are the opportunities for career progression?
Tune into this episode of The Cancer Researcher Podcast for an insightful conversation with our three expert guests who each work in scientific management in different positions and sectors.
Our guests in this episode:
Lynn Turner, Director of Research at Worldwide Cancer Research
Olivia Tort, International Project Manager at IRB Barcelona
Javier Carmona, Head of Scientific Strategy and Translational Programs at Vall d'Hebron Institute of Oncology
Access transcripts for all our episodes at magazine.eacr.org/podcast.
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Trailer
Welcome to The Cancer Researcher Podcast, from the European Association for Cancer Research.
By cancer researchers, for cancer researchers. Join us as we sit down with renowned researchers from around the world to discuss their personal experiences and insights on navigating a career in cancer research.
Whether you’re dealing with imposter syndrome or trying to figure out your next career step, this podcast offers valuable advice and powerful examples from the experts themselves to help you succeed in the world of cancer research. Join us monthly for an enlightening and empowering journey towards a fulfilling career in science.
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