Flot.bio x Philip Hemme

• Philipp Baaske, NanoTemper 🇩🇪 | Bootstrapping in Biotech | E29 [Sponsored]

  We’re in Munich with Philipp Baaske, one of the best life science tools founder in Europe.We talked about the lessons building this life science tools business specialized in protein interactions. We also talked about the difficulty and rewards of entrepreneurship, and the impact of life science tools.___This episode is sponsored by NanoTemper Technologies, which performs protein characterization. Learn more at https://bit.ly/flotbio_nanotemper___⭐️ ABOUT THE SPEAKERPhilipp Baaske, a German biophysicist, co-founded NanoTemper Technologies in 2008 with Stefan Duhr. He earned his PhD from Ludwig-Maximilians-University Munich, specializing in biophysics. Baaske pioneered MicroScale Thermophoresis, advancing drug discovery research. He was Co-CEO for 16 years before becoming Executive Chairman in 2024. An award-winning innovator, he supports biotech and entrepreneurship as a business angel.🔗 LINKS MENTIONEDAbout Nanotemper - https://nanotempertech.com/about/Thomas Ybert, DNA Script 🇫🇷 | DNA Printing & Synthesis | E27 - https://youtu.be/tF25lyAPUGI📜 TRANSCRIPT Read the full transcript here: coming soon💸 DONATEWe welcome donations from individuals and businesses to support our podcast and allow us to create even more content: https://www.paypal.me/PhilipHemme⭐️ SPONSORSHIP Ready to amplify your brand to influential leaders in biotech and biopharma? Contact [email protected] and unlock sponsorship opportunities in our podcasts!🫶 FOLLOW USNewsletter: http://eepurl.com/h_fnmHLinkedIn: https://www.linkedin.com/company/flot-bio/X (Twitter): https://x.com/FlotBio🙏 LIKE/FOLLOW/REVIEW Did you enjoy the episode? Please hit the like and subscribe button. Also, please let me know your thoughts in the comments below.🎙️ ABOUT FLOT.BIO Flot.bio is a show to watch the best Europeans in biotech to help you grow. Hosted by Philip Hemme. 20k monthly views. Free.⏰ TIMESTAMPS[00:02:01] Bootstrapping NanoTemper[00:06:30] The science behind NanoTemper[00:17:55] Venture capital or not[00:24:44] I’ve never had a job[00:28:40] Impact of Biotech on Cancer[00:33:40] Importance of Europe[00:43:00] Chinese expansion[00:47:26] Manufacturing in house[00:50:41] Next 10 years[01:07:38] Quick fire

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• Mathias Uhlen 🇸🇪 | Entrepreneurial Scientist, 26 times | E28

  We’re online 🇸🇪 with Mathias Uhlen, one of the best entrepreneurial scientists in Europe.We talked about the entrepreneurial mindset in academia. We also talked about AI for biology and why he doesn’t believe in the current anti-ageing drugs.⭐️ ABOUT THE SPEAKERLooking at the career of Mathias Uhlen can only leave you feeling impressed. He has co-founded or invested in 26 startups while having published over 800 papers, and creating the Human Protein Atlas, one of the most successful biology projects ever. He was also the Founding Director of Science for Life Laboratory (SciLifeLab), a national project with the Swedish government to help technology and data-driven research in support of European life science research. 🔗 LINKS MENTIONED- New innovation award celebrates entrepreneurs who have taken on big challenges: https://www.kth.se/en/om/nyheter/centrala-nyheter/nytt-innovationspris-hyllar-entreprenoren-som-tar-sig-an-stora-utmaningar-1.1049278- Jens Nielsen, BII | How to make translation of life science research work | E12: https://flot.bio/episode/jens-nielsen-translation-of-life-science-research/📜 TRANSCRIPTRead the full transcript here: https://flot.bio/episode/mathias-uhlen-entrepreneur/💸 DONATEWe welcome donations from individuals and businesses to support our podcast and allow us to create even more content: https://www.paypal.me/PhilipHemme⭐️ SPONSORSHIPReady to amplify your brand to influential leaders in biotech and biopharma? Contact [email protected] and unlock sponsorship opportunities in our podcasts!🫶 FOLLOW US- Newsletter: http://eepurl.com/h_fnmH- LinkedIn: https://www.linkedin.com/company/flot-bio/- X (Twitter): https://x.com/FlotBio🙏 LIKE/FOLLOW/REVIEWDid you enjoy the episode? Please hit the like and subscribe button. Also, please let me know your thoughts in the comments below.🎙️ ABOUT FLOT.BIOFlot.bio is a show to watch the best Europeans in biotech to help you grow. Hosted by Philip Hemme. 20k monthly views. Free.⏰ TIMESTAMPS- [00:00:00] Intro- [00:02:05] How Mathias Uhlen co-founded 26 startups- [00:10:55] Entrepreneurial mindset- [00:15:10] Entrepreneurial scientist in Europe- [00:18:43] Developing tools for research in biotech- [00:20:53] Human Protein Atlas- [00:24:55] AI for biology and AlphaCell- [00:34:35] Lessons for younger academics- [00:37:24] Combination of tech and biology- [00:40:57] False promises of anti-ageing- [00:44:48] Quickfire- [00:48:35] Thanks for listening

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  49:25
• Thomas Ybert, DNA Script 🇫🇷 | DNA Printing & Synthesis | E27

  We’re online 🇫🇷 with Thomas Ybert, the co-founder of DNA Script, the leading biotech for DNA printing of oligos. We talked about the commercialization of the first DNA printer. We also talked about company building at large and how to expand to the US successfully. ⭐️ ABOUT THE SPEAKER At just 30 years old, Thomas Ybert co-founded DNA Script in 2014 in Paris. Previously he worked in R&D at Sanofi before joining Total in the New Energies Division where he contributed to the bio jet-fuel project in collaboration with Amyris. It was here he developed his passion for manufacturing synthetic DNA which moved him from the world of academic research to a startup. 🔗 LINKS MENTIONED From 3 nucleotides to being a cornerstone technology for precision medicine, my journey creating an Enzymatic DNA Synthesis technology and company: https://www.linkedin.com/pulse/from-3-nucleotides-being-cornerstone-technology-precision-ybert-ykw3c?trackingId=HIpMVK4lTiOPcxcWeSsI4w%3D%3D&lipi=urn%3Ali%3Apage%3Ad_flagship3_search_srp_all%3BIW0XygKqT4Wbnq6s0mNP7Q%3D%3D DNA Script to Unveil Industry’s Most Versatile On-site, On-Demand DNA Printer at the World’s Largest Synthetic Biology Conference: https://www.biospace.com/dna-script-to-unveil-industry-s-most-versatile-on-site-on-demand-dna-printer-at-the-world-s-largest-synthetic-biology-conference DNA Script Appoints Marc Montserrat as CEO to Drive Long-Term Commercial Growth for Groundbreaking Enzymatic DNA Synthesis Platform: https://www.dnascript.com/press-releases/dna-script-appoints-marc-montserrat-as-ceo-to-drive-long-term-commercial-growth-for-groundbreaking-enzymatic-dna-synthesis-platform/ Towards Longer, Purer Oligonucleotides Thanks to Enzymatic DNA Synthesis: https://www.synbiobeta.com/read/towards-longer-purer-oligonucleotides-thanks-to-enzymatic-dna-synthesis 📜 TRANSCRIPT Read the full transcript here: https://flot.bio/episode/thomas-ybert-dna-script-dna-printing/ 💸 DONATE We welcome donations from individuals and businesses to support our podcast and allow us to create even more content: https://www.paypal.me/PhilipHemme ⭐️ SPONSORSHIP Ready to amplify your brand to influential leaders in biotech and biopharma? Contact [email protected] and unlock sponsorship opportunities in our podcasts! 🫶 FOLLOW US Newsletter: http://eepurl.com/h_fnmH LinkedIn: https://www.linkedin.com/company/flot-bio/ X (Twitter): https://x.com/FlotBio 🙏 LIKE/FOLLOW/REVIEW Did you enjoy the episode? Please hit the like and subscribe button. Also, please let me know your thoughts in the comments below. 🎙️ ABOUT FLOT.BIO Flot.bio is a show to watch the best Europeans in biotech to help you grow. Hosted by Philip Hemme. 20k monthly views. Free. ⏰ TIMESTAMPS [00:00:00] Intro [00:02:06] One decade after the inception of DNA Printing [00:12:35] The problem DNA printing is solving [00:22:44] Reaching €20M sales [00:25:09] Productizing a science breakthrough [00:32:49] Thomas Ybert's transition from CEO to CSO [00:39:53] Early US expansion for DNA Script [00:49:22] Next steps for DNA Script [00:51:18] Quickfire [00:57:50] Thanks for listening

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  58:36
• Gunilla Osswald, BioArctic 🇸🇪 | Leqembi, Alzheimer’s disease | E26

  We’re at BIO-Europe in Stockholm 🇸🇪 with Gunilla Osswalld, the CEO of BioArctic, the inventor of one of the only drugs that have worked for Alzheimer's. We talked about the science and business behind Leqembi. We also talked about the Alzheimer’s field at large and transitioning from big pharma to biotech. — — — Thank you to today’s sponsor, Turbine, who is organizing a free Techbio event at JPM25 and is inviting you to join. Click the link to RSVP and secure one of the limited spots: https://www.turbine.ai/jpm25-event-registration — — — ⭐️ ABOUT THE SPEAKER Gunilla joined BioArctic in 2013 after many successful years in executive positions at Astra/AstraZeneca, including Vice President for the product portfolio of neurodegenerative diseases. Since joining BioArctic, the largest Swedish biotech, Leqembi, one of the only successful drugs for Alzheimer’s was approved. This was an invention of BioArctic that Eisai and Biogen have commercialized. This is a particularly impressive feat considering 98% of Alzheimer’s drugs fail. 🔗 LINKS MENTIONED- The CEO of BioArctic talks Leqembi and what's next in Alzheimer's, Parkinson's, ALS, and more: https://www.biotechtv.com/post/bioarctic-gunilla-osswald-september-21-2024 - Roche sees rapid amyloid clearing in Alzheimer's study, adjusts protocol after patient death: https://www.fiercebiotech.com/biotech/roche-sees-rapid-amyloid-clearing-early-alzheimers-study - Edwin Moses | How to build large biotech platforms | E13: https://flot.bio/episode/edwin-moses-biotech-platforms/ 📜 TRANSCRIPT Read the full transcript here: https://flot.bio/episode/gunilla-osswald-bioarctic-alzheimers/ 💸 DONATE We welcome donations from individuals and businesses to support our podcast and allow us to create even more content: https://www.paypal.me/PhilipHemme ⭐️ SPONSORSHIP Ready to amplify your brand to influential leaders in biotech and biopharma? Contact [email protected] and unlock sponsorship opportunities in our podcasts! 🫶 FOLLOW US - Newsletter: http://eepurl.com/h_fnmH - LinkedIn: https://www.linkedin.com/company/flot-bio/ - X (Twitter): https://x.com/FlotBio 🙏 LIKE/FOLLOW/REVIEW Did you enjoy the episode? Please hit the like and subscribe button. Also, please let me know your thoughts in the comments below. 🎙️ ABOUT FLOT.BIO Flot.bio is a show to watch the best Europeans in biotech to help you grow. Hosted by Philip Hemme. 15k monthly views. Free. ⏰ TIMESTAMPS [00:00:00] Intro [00:02:24] Leqembi and BioArctic [00:10:40] Side effects of Leqembi for Alzheimer's treatment [00:17:03] Passing the blood-brain barrier for better Alzheimer's treatments [00:21:00] Market access for Leqembi in Europe [00:27:03] Gunilla Osswald's commitment to patients [00:31:55] Leaving AstraZeneca, transitioning to biotech [00:38:42] Unique culture at BioArctic [00:42:26] Alzheimer's field in Europe and at large [00:48:20] Quickfire [00:53:42] Thanks for listening

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  54:25
• Sean Marett 🇩🇪 | BioNTech, Art of Dealmaking | E25

  We’re in Hamburg with Sean Marett, who has been instrumental to the success of BioNTech for 12 years. We talked about the secrets behind BioNTech’s success. We also talked about the art of dealmaking and working with China. ⭐️ ABOUT THE SPEAKER Sean joined BioNTech in 2012 as part of the Management Board. He was instrumental in the growth of the company and global expansion through business development and product commercialization. Prior to BioNTech Sean worked in top companies such as GlaxoSmithKline, Pfizer, Evotec, and Lorantis. I first met Sean in 2015 in Berlin, when BioNTech had no website, but was already the largest private biotech in Europe. Now Sean has retired from BioNTech after 12 years but still aids the company as a specialist consultant. 🔗 LINKS MENTIONED - BioNTech Announces Planned Retirement of Sean Marett: https://investors.biontech.de/news-releases/news-release-details/biontech-announces-planned-retirement-sean-marett - BioNTech pays $800M to take control of potential Keytruda killer: https://www.fiercebiotech.com/biotech/biontech-pays-800m-take-control-potential-keytruda-killer - Sean Marett, COO at BioNTech, on the Future of mRNA Therapies - 2015: https://www.youtube.com/watch?v=6zrDKRvsAEU 📜 TRANSCRIPT Read the full transcript here: 💸 DONATE We welcome donations from individuals and businesses to support our podcast and allow us to create even more content: https://www.paypal.me/PhilipHemme ⭐️ SPONSORSHIP Ready to amplify your brand to influential leaders in biotech and biopharma? Contact [email protected] and unlock sponsorship opportunities in our podcasts! 🫶 FOLLOW US - Newsletter: http://eepurl.com/h_fnmH - LinkedIn: https://www.linkedin.com/company/flot-bio/ - X (Twitter): https://x.com/FlotBio 🙏 LIKE/FOLLOW/REVIEW Did you enjoy the episode? Please hit the like and subscribe button. Also, please let me know your thoughts in the comments below. 🎙️ ABOUT FLOT.BIO Flot.bio is a show to watch the best Europeans in biotech to help you grow. Hosted by Philip Hemme. 15k monthly views. Free. ⏰ TIMESTAMPS - [00:00:00] Intro - [00:01:45] Sean Marett stepping down as CBO of BioNTech - [00:05:10] From Pfizer to BioNTech - [00:15:28] Building a biotech in Mainz - [00:29:02] The art of biotech dealmaking - [00:45:29] Mistakes in dealmaking - [00:57:45] Biotech dealmaking in China - [01:04:25] Managing energy - [01:08:17] Quickfire - [01:13:57] Thanks for listening

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  1:14:55

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